Professor John Isaacs is a clinical scientist with a passion for translational research driven by his curiosity and the needs of his patients. He began his medical career at St George’s Hospital in London, taking in a stint at Beth Israel Hospital in Boston as part of the Hammersmith-Harvard exchange programme, before completing his PhD at Cambridge. It was at Addenbrooke’s Hospital in Cambridge that John met a patient who changed the direction of his research — and his life — forever. That meeting spurred him on to become one of the best known names in his new-found field — Clinical Rheumatology. He went on to become Professor of Clinical Rheumatology and Director of the Institute of Cellular Medicine at Newcastle University. In his spare time, John enjoys music and running. He is a regular Great North Run participant, and plays saxophone for “The Joy of Sax” based at the Sage Gateshead.